Aetiology
Renal
infections arise in the following ways:
Haematogenous infection from
primary site in the tonsils or carious teeth or from cutaneous infections,
particularly boils or carbuncle.
Renal tuberculosis occurs by
blood borne spread from lymph nodes in the neck, chest or abdomen.
Ascending infection in the
urinary tract is the most common route, and it is most likely to occur when there
is vesicoureteric reflux. Urinary stasis and the presence of calculi are common
contributory factors.
Kidney
infections are:
*Acute
pyelonephritis:
In childhood
In pregnancy
With urinary obstruction
*Chronic
pyelonephritis:
Reflux nephropathy
*Pyonephrosis
*Renal
abscess
*Perinephric
abscess
Bacteria
Escherichia coli and other Gram-regative
organisms are commonly responsible. When Streptococcusfaecalis
is present it is usually accompanied by other organisms.
In
E. coli and Streptococcal infections the urine is acidic.
Proteus spp. and Staphylococci split urea to form ammonia, which makes the urine
alkaline and promotes the formation of calculi.
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